Iron-porphyrin Catalyzed Carbene Transfer Reactions – an Evolution fro Biomimetic Catalysis towards Chemistry-inspired Non-natural Reactivities of Enzymes
ChemCatChem 2020, 10.1002/cctc.201901565
Bioinspired, synthetic porphyrin complexes are important catalysts in organic synthesis and play a pivotal role in efficient carbene transfer reactions. The advances in this research area stimulated recent, “chemo‐inspired” developments in biocatalysis. Today, both synthetic iron complexes and enzymes play an important role to conduct carbene transfer reactions. The advances and potential developments in both research areas are discussed in this concept article.
Metal: FeLigand type: PorphyrinHost protein: ---Anchoring strategy: ---Optimization: Chemical & geneticReaction: Carbene insertionMax TON: ---ee: ---PDB: ---Notes: ---