2 publications

2 publications

Improving the Catalytic Performance of an Artificial Metalloenzyme by Computational Design

Baker, D.; Ward, T. R.

J. Am. Chem. Soc., 2015, 10.1021/jacs.5b06622


Metal: Ir
Ligand type: Cp*; Pyridine sulfonamide
Anchoring strategy: Supramolecular
Optimization: Genetic
Max TON: 100
ee: 96
PDB: ---
Notes: ---

Redox-Switchable Siderophore Anchor Enables Reversible Artificial Metalloenzyme Assembly

Duhme-Klair, A. K.; Wilson, K. S.

Nat. Catal., 2018, 10.1038/s41929-018-0124-3


Metal: Ir
Ligand type: Cp*; Pyridine sulfonamide
Host protein: CeuE
Anchoring strategy: Supramolecular
Optimization: Chemical & genetic
Max TON: ---
ee: 35.4
PDB: 5OD5
Notes: Redox switchable iron(III)-azotochelin anchor