4 publications

4 publications

A Structural View of Synthetic Cofactor Integration into [FeFe]-Hydrogenases

Apfel, U.-P.; Happe, T.; Kurisu, G.

Chem. Sci., 2016, 10.1039/C5SC03397G


Metal: Fe
Ligand type: CN; CO; Dithiolate
Anchoring strategy: Dative
Optimization: Chemical
Reaction: H2 evolution
Max TON: ---
ee: ---
PDB: 4XDC
Notes: H2 evolution activity of the ArM: 2874 (mmol H2)*min-1*(mg protein)-1.

Hybrid [FeFe]-Hydrogenases with Modified Active Sites Show Remarkable Residual Enzymatic Activity

Lubitz, W.; Reijerse, E.

Biochemistry, 2015, 10.1021/bi501391d


Metal: Fe
Ligand type: CN; CO; Dithiolate
Anchoring strategy: Dative
Optimization: Chemical
Max TON: ---
ee: ---
PDB: ---
Notes: H2 evolution: TOF = 450 s-1. H2 oxidation: TOF = 150 s-1.

Photoinduced Hydrogen Evolution Catalyzed by a Synthetic Diiron Dithiolate Complex Embedded within a Protein Matrix

Onoda, A.

ACS Catal., 2014, 10.1021/cs500392e


Metal: Fe
Ligand type: Carbonyl; Dithiolate
Host protein: Nitrobindin (Nb)
Anchoring strategy: Covalent
Optimization: ---
Reaction: H2 evolution
Max TON: 130
ee: ---
PDB: ---
Notes: ---

Spontaneous Activation of [FeFe]-Hydrogenases by an Inorganic [2Fe] Active Site Mimic

Happe, T.

Nat. Chem. Biol., 2013, 10.1038/Nchembio.1311


Metal: Fe
Ligand type: CN; CO; Dithiolate
Anchoring strategy: Dative
Optimization: Chemical
Reaction: H2 evolution
Max TON: ---
ee: ---
PDB: ---
Notes: ---