2 publications

2 publications

Receptor-Based Artificial Metalloenzymes on Living Human Cells

Ghattas, W.; Mahy, J.-P.

J. Am. Chem. Soc., 2018, 10.1021/jacs.8b04326


Metal: Cu
Ligand type: Phenanthroline
Anchoring strategy: Supramolecular
Optimization: Chemical & genetic
Max TON: 24
ee: 35
PDB: ---
Notes: ---

Synthesis of a Heterogeneous Artificial Metallolipase with Chimeric Catalytic Activity

Filice, M.

Chem. Commun., 2015, 10.1039/C5CC02450A


Metal: Cu
Ligand type: Phenanthroline
Anchoring strategy: Covalent
Optimization: Genetic
Max TON: 411
ee: 92
PDB: ---
Notes: ArM is immobilized on Sepabeads. Endo/exo = 93.5%

Metal: Cu
Ligand type: Phenanthroline
Anchoring strategy: Covalent
Optimization: Genetic
Reaction: Reduction
Max TON: ---
ee: ---
PDB: ---
Notes: Cascade reaction: Ester hydrolysis (natural function of the host protein) followed by reduction (function of the designed ArM).