5 publications

5 publications

Engineered Metal Regulation of Trypsin Specificity

Craik, C. S.

Biochemistry, 1995, 10.1021/bi00007a010


Metal: Zn
Ligand type: Amino acid
Host protein: Trypsin
Anchoring strategy: Dative
Optimization: Genetic
Max TON: ---
ee: ---
PDB: ---
Notes: Substrate specificty

Metal: Ni
Ligand type: Amino acid
Host protein: Trypsin
Anchoring strategy: Dative
Optimization: Genetic
Max TON: ---
ee: ---
PDB: ---
Notes: Substrate specificty

Going Beyond Structure: Nickel-Substituted Rubredoxin as a Mechanistic Model for the [NiFe] Hydrogenases

Shafaat, H. S.

J. Am. Chem. Soc., 2018, 10.1021/jacs.8b05194


Metal: Ni
Ligand type: Amino acid
Host protein: Rubredoxin (Rd)
Anchoring strategy: Metal substitution
Optimization: Genetic
Reaction: H2 evolution
Max TON: ---
ee: ---
PDB: ---
Notes: TOF = 149 s-1

Metal Incorporated Horseradish Peroxidase (HRP) Catalyzed Oxidation of Resveratrol: Selective Dimerization or Decomposition

Pan, Y.

RSC Adv., 2013, 10.1039/c3ra43784a


Metal: Ca; Co; Mn; Ni; Zn
Ligand type: Undefined
Anchoring strategy: Undefined
Optimization: Chemical
Reaction: Oxidation
Max TON: ---
ee: ---
PDB: ---
Notes: Oxidation of resveratrol. Dimerisation product obtained.

Nickel-Substituted Rubredoxin as a Minimal Enzyme Model for Hydrogenase

Shafaat, H. S.

J. Phys. Chem. Lett., 2015, 10.1021/acs.jpclett.5b01750


Metal: Ni
Ligand type: Tetrathiolate
Host protein: Rubredoxin (Rd)
Anchoring strategy: Metal substitution
Optimization: ---
Reaction: H2 evolution
Max TON: 300
ee: ---
PDB: ---
Notes: ---

Protein Delivery of a Ni Catalyst to Photosystem I for Light-Driven Hydrogen Production

Tiede, D. M.; Utschig, L. M.

J. Am. Chem. Soc., 2013, 10.1021/ja405277g


Metal: Ni
Ligand type: Phosphine
Host protein: Flavodoxin (Fld)
Anchoring strategy: Supramolecular
Optimization: ---
Reaction: H2 evolution
Max TON: 94
ee: ---
PDB: ---
Notes: Recalculated TON

Metal: Ni
Ligand type: Phosphine
Host protein: Photosystem I (PSI)
Anchoring strategy: Undefined
Optimization: ---
Reaction: H2 evolution
Max TON: 1870
ee: ---
PDB: ---
Notes: Recalculated TON