1 publication

1 publication

A "Broad Spectrum" Carbene Transferase for Synthesis of Chiral α-Trifluoromethylated Organoborons

Roelfes, G.

ACS Cent. Sci. 2019, 5, 206-208, 10.1021/acscentsci.9b00015

Directed evolution generated an enzyme for the enantioselective synthesis of α-trifluoromethylated organoborons—potentially attractive synthons for fluorinated compounds.

Metal: Fe
Ligand type: Porphyrin
Host protein: Cytochrome c
Anchoring strategy: Native
Optimization: Genetic
Reaction: B-H insertion
Max TON: 2900
ee: 95
PDB: ---
Notes: ---