1 publication

1 publication

A Protein-Rhodium Complex as an Efficient Catalyst for Two-Phase Olefin Hydroformylation

Marchetti, M.

Tetrahedron Lett. 2000, 41, 3717-3720, 10.1016/S0040-4039(00)00473-1

A highly efficient and chemoselective biphasic hydroformylation of olefins was accomplished using water soluble complexes formed by the interaction between Rh(CO)2(acac) and human serum albumin (HSA), a readily available water soluble protein. A new type of shape-selectivity was observed in the hydroformylation of sterically hindered olefins.

Metal: Rh
Ligand type: Acac; CO2
Anchoring strategy: Undefined
Optimization: ---
Reaction: Hydroformylation
Max TON: ~600
ee: ---
PDB: ---
Notes: ---