3 publications

3 publications

Artificial Metalloenzymes with the Neocarzinostatin Scaffold: Toward a Biocatalyst for the Diels–Alder Reaction

Mahy, J.-P.; Ricoux, R.

ChemBioChem, 2016, 10.1002/cbic.201500445


Metal: Cu
Ligand type: Phenanthroline
Anchoring strategy: Supramolecular
Optimization: ---
Max TON: 33
ee: ---
PDB: ---
Notes: Up to endo/exo ratio 62:38

Neocarzinostatin-Based Hybrid Biocatalysts for Oxidation Reactions

Mahy, J.-P.; Ricoux, R.

Dalton Trans., 2014, 10.1039/c4dt00151f


Metal: Fe
Ligand type: Porphyrin
Anchoring strategy: Supramolecular
Optimization: ---
Reaction: Sulfoxidation
Max TON: 6
ee: 13
PDB: ---
Notes: ---

Neocarzinostatin-Based Hybrid Biocatalysts with a RNase like Activity

Mahy, J.-P.; Ricoux, R.

Bioorg. Med. Chem., 2014, 10.1016/j.bmc.2014.05.063


Metal: Zn
Ligand type: Poly-pyridine
Anchoring strategy: Supramolecular
Optimization: ---
Max TON: ---
ee: ---
PDB: ---
Notes: kcat/KM = 13.6 M-1 * s-1