1 publication

1 publication

Iron-porphyrin Catalyzed Carbene Transfer Reactions – an Evolution fro Biomimetic Catalysis towards Chemistry-inspired Non-natural Reactivities of Enzymes

Koenigs, R.M.; Weissenborn, M.J.

ChemCatChem 2020, 10.1002/cctc.201901565

Bioinspired, synthetic porphyrin complexes are important catalysts in organic synthesis and play a pivotal role in efficient carbene transfer reactions. The advances in this research area stimulated recent, “chemo‐inspired” developments in biocatalysis. Today, both synthetic iron complexes and enzymes play an important role to conduct carbene transfer reactions. The advances and potential developments in both research areas are discussed in this concept article.

Metal: Fe
Ligand type: Porphyrin
Host protein: ---
Anchoring strategy: ---
Optimization: Chemical & genetic
Reaction: Carbene insertion
Max TON: ---
ee: ---
PDB: ---
Notes: ---