10 publications

10 publications

Aqueous Phase Transfer Hydrogenation of Aryl Ketones Catalysed by Achiral Ruthenium(II) and Rhodium(III) Complexes and their Papain Conjugates

Salmain, M.

Appl. Organomet. Chem., 2013, 10.1002/aoc.2929


Metal: Rh
Ligand type: Cp*; Poly-pyridine
Host protein: Papain (PAP)
Anchoring strategy: Covalent
Optimization: Chemical
Reaction: Hydrogenation
Max TON: 96
ee: 15
PDB: ---
Notes: ---

Artificial Metalloenzymes Containing an Organometallic Active Site

Review

Onoda, A.; Salmain, M.

Bioorganometallic Chemistry: Applications in Drug Discovery, Biocatalysis, and Imaging, 2014, 10.1002/9783527673438.ch10


Notes: Book chapter

Artificial Metalloenzymes Derived from Bovine β-Lactoglobulin for the Asymmetric Transfer Hydrogenation of an Aryl Ketone – Synthesis, Characterization and Catalytic Activity

Salmain, M.

Dalton Trans., 2014, 10.1039/c3dt53253d


Metal: Rh
Ligand type: Cp*; Poly-pyridine
Host protein: ß-lactoglobulin
Anchoring strategy: Supramolecular
Optimization: Chemical
Reaction: Hydrogenation
Max TON: 14
ee: 32
PDB: ---
Notes: ---

Chemically Engineered Papain as Artificial Formate Dehydrogenase for NAD(P)H Regeneration

Salmain, M.

Org. Biomol. Chem., 2011, 10.1039/c1ob05482a


Metal: Rh
Ligand type: Cp*; Poly-pyridine
Host protein: Papain (PAP)
Anchoring strategy: Covalent
Optimization: Chemical
Reaction: Hydrogenation
Max TON: ---
ee: ---
PDB: ---
Notes: TOF = 52.1 h-1 for NAD+

Enantioselective Transfer Hydrogenation of Ketone Catalysed by Artificial Metalloenzymes Derived from Bovine β-Lactoglobulin

Salmain, M.

Chem. Commun., 2012, 10.1039/c2cc36980j


Metal: Rh
Ligand type: Cp*; Poly-pyridine
Host protein: ß-lactoglobulin
Anchoring strategy: Supramolecular
Optimization: Chemical
Reaction: Hydrogenation
Max TON: 34
ee: 26
PDB: ---
Notes: ---

Piano-Stool d(6)-Rhodium(III) Complexes of Chelating Pyridine-Based Ligands and their Papain Bioconjugates for the Catalysis of Transfer Hydrogenation of Aryl Ketones in Aqueous Medium

Mangiatordi, G. F.; Salmain, M.

J. Mol. Catal. B: Enzym., 2015, 10.1016/j.molcatb.2015.10.007


Metal: Rh
Ligand type: Cp*; Phenanthroline
Host protein: Papain (PAP)
Anchoring strategy: Covalent
Optimization: Chemical
Max TON: 30
ee: 9
PDB: ---
Notes: ---

Metal: Rh
Ligand type: Cp*; Di(2-pyridyl)
Host protein: Papain (PAP)
Anchoring strategy: Covalent
Optimization: Chemical
Max TON: 20
ee: 5
PDB: ---
Notes: ---

Piano-Stool d(6)-Rhodium(III) Complexes of Chelating Pyridine-Based Ligands and their Papain Bioconjugates for the Catalysis of Transfer Hydrogenation of Aryl Ketones in Aqueous Medium

Mangiatordi, G. F.; Salmain, M.

J. Mol. Catal. B: Enzym., 2015, 10.1016/j.molcatb.2015.10.007


Metal: Rh
Ligand type: Cp*; Phenanthroline
Host protein: Papain (PAP)
Anchoring strategy: Covalent
Optimization: Chemical
Max TON: 30
ee: 9
PDB: ---
Notes: ---

Metal: Rh
Ligand type: Cp*; Di(2-pyridyl)
Host protein: Papain (PAP)
Anchoring strategy: Covalent
Optimization: Chemical
Max TON: 20
ee: 5
PDB: ---
Notes: ---

Proteins as Macromolecular Ligands for Metal-Catalysed Asymmetric Transfer Hydrogenation of Ketones in Aqueous Medium

Salmain, M.

Eur. J. Inorg. Chem., 2018, 10.1002/ejic.201701359


Metal: Ru
Ligand type: Benzene derivatives
Anchoring strategy: Undefined
Optimization: ---
Max TON: 43
ee: 82
PDB: ---
Notes: ---

Metal: Rh
Ligand type: Cp*
Anchoring strategy: Undefined
Optimization: ---
Max TON: 16
ee: 14
PDB: ---
Notes: ---

Metal: Ir
Ligand type: Cp*
Anchoring strategy: Undefined
Optimization: ---
Max TON: 20
ee: 16
PDB: ---
Notes: ---

Supramolecular Anchoring of NCN-Pincer Palladium Complexes into a β-Barrel Protein Host: Molecular-Docking and Reactivity Insights

Salmain, M.; Thorimbert, S.

Eur. J. Inorg. Chem., 2017, 10.1002/ejic.201700365


Metal: Pd
Ligand type: NCN-Pincer (amines)
Host protein: β-lactoglobulin (βLG)
Anchoring strategy: Supramolecular
Optimization: Chemical
Reaction: Aldol condensation
Max TON: 4.9
ee: 0
PDB: ---
Notes: Aldol condensation of methyl isocyanoacetate and benzaldehyde (trans/cis = 38:62)

(η6-Arene) Ruthenium(II) Complexes and Metallo-Papain Hybrid as Lewis Acid Catalysts of Diels–Alder Reaction in Water

Salmain, M.

Dalton Trans., 2010, 10.1039/c001630f

Covalent embedding of a (η6-arene) ruthenium(II) complex into the protein papain gives rise to a metalloenzyme displaying a catalytic efficiency for a Lewis acid-mediated catalysed Diels–Alder reaction enhanced by two orders of magnitude in water.


Metal: Ru
Ligand type: Benzene; Phenanthroline
Host protein: Papain (PAP)
Anchoring strategy: Covalent
Optimization: Chemical
Max TON: 440
ee: ---
PDB: ---
Notes: TOF = 220 h-1