Chalcogenide Substitution in the [2Fe] Cluster of [FeFe]-Hydrogenases Conserves High Enzymatic Activity
Dalton Trans. 2017, 46, 16947-16958, 10.1039/C7DT03785F
Combination of biological and chemical methods allow for creation of [FeFe]-hydrogenases with an artificial synthetic cofactor.
Metal: FeLigand type: CN; CO; DiselenolateHost protein: [FeFe]-hydrogenase from C. pasteurianum (CpI)Anchoring strategy: DativeOptimization: ChemicalReaction: H2 evolutionMax TON: ---ee: ---PDB: 5OEFNotes: ---