5 publications

5 publications

Antibody-Metalloporphyrin Catalytic Assembly Mimics Natural Oxidation Enzymes

Keinan, E.

J. Am. Chem. Soc., 1999, 10.1021/ja990314q


Metal: Ru
Ligand type: Porphyrin
Host protein: Antibody SN37.4
Anchoring strategy: Supramolecular
Optimization: Chemical
Reaction: Sulfoxidation
Max TON: 750
ee: 43
PDB: ---
Notes: ---

Artificial Metalloenzymes based on Protein Cavities: Exploring the Effect of Altering the Metal Ligand Attachment Position by Site Directed Mutagenesis

Distefano, M. D.

Bioorg. Med. Chem. Lett., 1999, 10.1016/S0960-894X(98)00684-2


Metal: Cu
Ligand type: Phenanthroline
Anchoring strategy: Covalent
Optimization: Genetic
Max TON: 1 to 4
ee: 61 to 94
PDB: ---
Notes: Varied attachment position

Catalytic Hydrogenation of Itaconic Acid in a Biotinylated Pyrphos-Rhodium(I) System in a Protein Cavity

Chan, A. S. C.

Tetrahedron: Asymmetry, 1999, 10.1016/S0957-4166(99)00193-7


Metal: Rh
Ligand type: Phosphine
Host protein: Avidin (Av)
Anchoring strategy: Supramolecular
Optimization: ---
Reaction: Hydrogenation
Max TON: 31
ee: 48
PDB: ---
Notes: ---

Peroxidase Activity of Myoglobin is Enhanced by Chemical Mutation of Heme-Propionates

J. Am. Chem. Soc., 1999, 10.1021/ja9841005


Metal: Fe
Host protein: Myoglobin (Mb)
Anchoring strategy: Reconstitution
Optimization: ---
Max TON: ---
ee: ---
PDB: ---
Notes: ---

Studies of the Reactivity of Artificial Peroxidase-Like Hemoproteins Based on Antibodies Elicited Against a Specifically Designed ortho-Carboxy Substituted Tetraarylporphyrin

Mahy, J.-P.

FEBS Lett., 1999, 10.1016/S0014-5793(98)01703-7


Metal: Fe
Ligand type: Porphyrin
Host protein: Antibody 13G10
Anchoring strategy: Supramolecular
Optimization: ---
Max TON: ---
ee: ---
PDB: ---
Notes: TOF = 4.7 min-1