1 publication
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An Artificial Imine Reductase Based on the Ribonuclease S Scaffold
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ChemCatChem 2014, 6, 736-740, 10.1002/cctc.201300995
Dative anchoring of a piano‐stool complex within ribonuclease S resulted in an artificial imine reductase. The catalytic performance was modulated upon variation of the coordinating amino acid residues in the S‐peptide. Binding of Cp*Ir (Cp*=C5Me5) to the native active site resulted in good conversions and moderate enantiomeric excess values for the synthesis of salsolidine.
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