1 publication
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Asymmetric Hydrogenation with Antibody-Achiral Rhodium Complex
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Org. Biomol. Chem. 2006, 4, 3571, 10.1039/B609242J
Monoclonal antibodies have been elicited against an achiral rhodium complex and this complex was used in the presence of a resultant antibody, 1G8, for the catalytic hydrogenation of 2-acetamidoacrylic acid to produce N-acetyl-L-alanine in high (>98%) enantiomeric excess.
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