11 publications

11 publications

Coordinated Design of Cofactor and Active Site Structures in Development of New Protein Catalysts

Watanabe, Y.

J. Am. Chem. Soc., 2005, 10.1021/ja045995q


Metal: Mn
Ligand type: Salophen
Host protein: Myoglobin (Mb)
Anchoring strategy: Reconstitution
Optimization: Chemical & genetic
Max TON: ---
ee: ---
PDB: 1V9Q
Notes: ---

Metal: Cr
Ligand type: Salophen
Host protein: Myoglobin (Mb)
Anchoring strategy: Reconstitution
Optimization: Chemical & genetic
Max TON: ---
ee: ---
PDB: 1J3F
Notes: ---

Metal: Mn
Ligand type: Salen
Host protein: Myoglobin (Mb)
Anchoring strategy: Reconstitution
Optimization: Chemical & genetic
Max TON: ---
ee: ---
PDB: ---
Notes: ---

Metal: Cr
Ligand type: Salen
Host protein: Myoglobin (Mb)
Anchoring strategy: Reconstitution
Optimization: Chemical & genetic
Max TON: ---
ee: ---
PDB: ---
Notes: ---

Crystal Structure and Peroxidase Activity of Myoglobin Reconstituted with Iron Porphycene

Inorg. Chem., 2006, 10.1021/ic061130x


Metal: Fe
Ligand type: Porphycene
Host protein: Myoglobin (Mb)
Anchoring strategy: Reconstitution
Optimization: ---
Max TON: ---
ee: ---
PDB: 1MBI
Notes: ---

Hybridization of Modified-Heme Reconstitution and Distal Histidine Mutation to Functionalize Sperm Whale Myoglobin

J. Am. Chem. Soc., 2004, 10.1021/ja038798k


Metal: Fe
Host protein: Myoglobin (Mb)
Anchoring strategy: Reconstitution
Optimization: Genetic
Max TON: ---
ee: ---
PDB: ---
Notes: ---

Meso-Unsubstituted Iron Corrole in Hemoproteins: Remarkable Differences in Effects on Peroxidase Activities between Myoglobin and Horseradish Peroxidase

J. Am. Chem. Soc., 2009, 10.1021/ja907428e


Metal: Fe
Ligand type: Corrole
Host protein: Myoglobin (Mb)
Anchoring strategy: Reconstitution
Optimization: ---
Max TON: ---
ee: ---
PDB: ---
Notes: ---

Metal: Fe
Ligand type: Corrole
Anchoring strategy: Reconstitution
Optimization: ---
Max TON: ---
ee: ---
PDB: ---
Notes: ---

Molecular Design of Heteroprotein Assemblies Providing a Bionanocup as a Chemical Reactor

Ueno, T.; Watanabe, Y.

Small, 2008, 10.1002/smll.200700855


Metal: Fe
Host protein: (gp27-gp5)3
Anchoring strategy: Cystein-maleimide
Optimization: ---
Max TON: ---
ee: ---
PDB: ---
Notes: ---

Peroxidase Activity of Cationic Metalloporphyrin-Antibody Complexes

Harada, A.

Chem. - Eur. J., 2004, 10.1002/chem.200305692


Metal: Fe
Ligand type: Porphyrin
Host protein: Antibody 12E11G
Anchoring strategy: Antibody
Optimization: ---
Max TON: ---
ee: ---
PDB: ---
Notes: ---

Peroxidase Activity of Myoglobin is Enhanced by Chemical Mutation of Heme-Propionates

J. Am. Chem. Soc., 1999, 10.1021/ja9841005


Metal: Fe
Host protein: Myoglobin (Mb)
Anchoring strategy: Reconstitution
Optimization: ---
Max TON: ---
ee: ---
PDB: ---
Notes: ---

Peroxidation of Pyrogallol by Antibody−Metalloporphyrin Complexes

Harada, A.

Inorg. Chem., 1997, 10.1021/ic9610849


Metal: Mn
Ligand type: Porphyrin
Host protein: Antibody 03-1
Anchoring strategy: Antibody
Optimization: ---
Max TON: 200
ee: ---
PDB: ---
Notes: ---

Metal: Fe
Ligand type: Porphyrin
Host protein: Antibody 03-1
Anchoring strategy: Antibody
Optimization: ---
Max TON: 300
ee: ---
PDB: ---
Notes: ---

Porphyrinoid Chemistry in Hemoprotein Matrix:  Detection and Reactivities of Iron(IV)-Oxo Species of Porphycene Incorporated into Horseradish Peroxidase

J. Am. Chem. Soc., 2007, 10.1021/ja074685f


Metal: Fe
Ligand type: Porphycene
Anchoring strategy: Reconstitution
Optimization: ---
Max TON: ---
ee: ---
PDB: ---
Notes: ---

Precise Design of Artificial Cofactors for Enhancing Peroxidase Activity of Myoglobin: Myoglobin Mutant H64D Reconstituted with a “Single-Winged Cofactor” is Equivalent to Native Horseradish Peroxidase in Oxidation Activity

Matsuo, T.

Chem. - Asian J., 2011, 10.1002/asia.201100107


Metal: Fe
Host protein: Myoglobin (Mb)
Anchoring strategy: Reconstitution
Optimization: Chemical & genetic
Max TON: ---
ee: ---
PDB: ---
Notes: ---

Preparation of Artificial Metalloenzymes by Insertion of Chromium(III) Schiff Base Complexes into apo-Myoglobin Mutants

Watanabe, Y.

Angew. Chem., Int. Ed., 2003, 10.1002/anie.200390256


Metal: Cr
Ligand type: Salophen
Host protein: Myoglobin (Mb)
Anchoring strategy: Reconstitution
Optimization: Genetic
Max TON: ---
ee: ---
PDB: ---
Notes: ---