14 publications

14 publications

Artificial Metalloenzyme for Enantioselective Sulfoxidation Based on Vanadyl-Loaded Streptavidin

Ward, T. R.

J. Am. Chem. Soc., 2008, 10.1021/ja8017219


Metal: V
Ligand type: Water
Host protein: Streptavidin (Sav)
Anchoring strategy: Supramolecular
Optimization: Genetic
Reaction: Sulfoxidation
Max TON: 27
ee: 93
PDB: ---
Notes: ---

Artificial Metalloenzymes as Selective Catalysts in Aqueous Media

Review

Ward, T. R.

Coord. Chem. Rev., 2008, 10.1016/j.ccr.2007.09.016


Notes: ---

Artificial Metalloenzymes for Asymmetric Allylic Alkylation on the Basis of the Biotin–Avidin Technology

Ward, T. R.

Angew. Chem., Int. Ed., 2008, 10.1002/anie.200703159


Metal: Pd
Ligand type: Phosphine
Host protein: Streptavidin (Sav)
Anchoring strategy: Supramolecular
Optimization: Chemical & genetic
Reaction: Allylic alkylation
Max TON: 10
ee: 93
PDB: ---
Notes: ---

Artificial Metalloenzymes for Enantioselective Catalysis Based on the Biotin-Avidin Technology

Review

Ward, T. R.

Chimia, 2008, 10.2533/chimia.2008.956


Notes: ---

Biosynthesis of a Site-Specific DNA Cleaving Protein

Schultz, P. G.

J. Am. Chem. Soc., 2008, 10.1021/ja804653f


Metal: Cu
Ligand type: Bipyridine
Anchoring strategy: ---
Optimization: Chemical & genetic
Max TON: ---
ee: ---
PDB: ---
Notes: Catabolite activator protein from E. coli

Metal: Fe
Ligand type: Bipyridine
Anchoring strategy: ---
Optimization: Chemical & genetic
Max TON: ---
ee: ---
PDB: ---
Notes: Catabolite activator protein from E. coli

Chemogenetic Protein Engineering: An Efficient Tool for the Optimization of Artificial Metalloenzymes

Review

Ward, T. R.

Chem. Commun., 2008, 10.1039/b806652c


Notes: ---

Control of the Coordination Structure of Organometallic Palladium Complexes in an Apo-Ferritin Cage

Ueno, T.; Watanabe, Y.

J. Am. Chem. Soc., 2008, 10.1021/ja802463a


Metal: Pd
Ligand type: Allyl
Host protein: Ferritin
Anchoring strategy: Dative
Optimization: ---
Reaction: Suzuki coupling
Max TON: ---
ee: ---
PDB: 2ZG7
Notes: ---

Functionalized Antibodies as Biosensing Materials and Catalysts

Review

Harada, A.

Chem. Lett., 2008, 10.1246/cl.2008.1184


Notes: ---

Hemozymes Peroxidase Activity Of Artificial Hemoproteins Constructed From the Streptomyces Lividans Xylanase A and Iron(III)-Carboxy-Substituted Porphyrins

Mahy, J.-P.

Bioconjug. Chem., 2008, 10.1021/bc700435a


Metal: Fe
Ligand type: Porphyrin
Host protein: Xylanase A (XynA)
Anchoring strategy: Supramolecular
Optimization: ---
Max TON: ---
ee: ---
PDB: ---
Notes: kcat/KM = 1083 M-1 * s-1

Molecular Design of Heteroprotein Assemblies Providing a Bionanocup as a Chemical Reactor

Ueno, T.; Watanabe, Y.

Small, 2008, 10.1002/smll.200700855


Metal: Fe
Host protein: (gp27-gp5)3
Anchoring strategy: Cystein-maleimide
Optimization: ---
Max TON: ---
ee: ---
PDB: ---
Notes: ---

Protein Scaffold of a Designed Metalloenzyme Enhances the Chemoselectivity in Sulfoxidation of Thioanisole

Lu, Y.

Chem. Commun., 2008, 10.1039/b718915j


Metal: Mn
Ligand type: Salen
Host protein: Myoglobin (Mb)
Anchoring strategy: Supramolecular
Optimization: Chemical & genetic
Reaction: Sulfoxidation
Max TON: 5.2
ee: 60
PDB: ---
Notes: Sperm whale myoglobin

Stereoselective Hydrogenation of Olefins Using Rhodium-Substituted Carbonic Anhydrase—A New Reductase

Kazlauskas, R. J.

Chem. - Eur. J., 2008, 10.1002/chem.200801673


Metal: Rh
Ligand type: COD
Anchoring strategy: Metal substitution
Optimization: Genetic
Reaction: Hydrogenation
Max TON: 15.8
ee: ---
PDB: ---
Notes: ---

Metal: Rh
Ligand type: COD
Anchoring strategy: Metal substitution
Optimization: Genetic
Reaction: Hydrogenation
Max TON: 80.5
ee: ---
PDB: 4CAC
Notes: PDB ID 4CAC = Structure of Zn containing hCAII

Synthesis of a New Estradiol–Iron Metalloporphyrin Conjugate Used to Build up a New Hybrid Biocatalyst for Selective Oxidations by the ‘Trojan Horse’ Strategy

Mahy, J.-P.

Tetrahedron Lett., 2008, 10.1016/j.tetlet.2008.01.022


Metal: Fe
Ligand type: Porphyrin
Host protein: Antibody 7A3
Anchoring strategy: Supramolecular
Optimization: ---
Reaction: Sulfoxidation
Max TON: 12
ee: 8
PDB: ---
Notes: ---

X-Ray Structure and Designed Evolution of an Artificial Transfer Hydrogenase

Ward, T. R.

Angew. Chem., Int. Ed., 2008, 10.1002/anie.200704865


Metal: Ru
Ligand type: Amino-sulfonamide; Benzene
Host protein: Streptavidin (Sav)
Anchoring strategy: Supramolecular
Optimization: Chemical & genetic
Max TON: 100
ee: 92
PDB: 2QCB
Notes: ---

Metal: Ru
Ligand type: Amino-sulfonamide; P-cymene
Host protein: Streptavidin (Sav)
Anchoring strategy: Supramolecular
Optimization: Chemical & genetic
Max TON: 97
ee: 96
PDB: 2QCB
Notes: ---