7 publications

7 publications

Artificial Metalloenzymes for the Diastereoselective Reduction of NAD+ to NAD2H

Ward, T. R.

Org. Biomol. Chem., 2015, 10.1039/c4ob02071e


Metal: Ir
Ligand type: Amino-sulfonamide; Cp*
Host protein: Streptavidin (Sav)
Anchoring strategy: Supramolecular
Optimization: ---
Max TON: ---
ee: ---
PDB: ---
Notes: ---

Asymmetric Hydrogenation with Antibody-Achiral Rhodium Complex

Harada, A.

Org. Biomol. Chem., 2006, 10.1039/B609242J


Metal: Rh
Ligand type: COD; Phosphine
Host protein: Antibody 1G8
Anchoring strategy: Antibody
Optimization: ---
Reaction: Hydrogenation
Max TON: ---
ee: ---
PDB: ---
Notes: ---

Carbonic Anhydrase II as Host Protein for the Creation of a Biocompatible Artificial Metathesase

Ward, T. R.

Org. Biomol. Chem., 2015, 10.1039/c5ob00428d


Metal: Ru
Ligand type: Carbene
Anchoring strategy: Dative
Optimization: Chemical & genetic
Reaction: Olefin metathesis
Max TON: 28
ee: ---
PDB: ---
Notes: Ring closing metathesis. 28 turnovers obtained under physiological conditions within 4 hours.

Chemically Engineered Papain as Artificial Formate Dehydrogenase for NAD(P)H Regeneration

Salmain, M.

Org. Biomol. Chem., 2011, 10.1039/c1ob05482a


Metal: Rh
Ligand type: Cp*; Poly-pyridine
Host protein: Papain (PAP)
Anchoring strategy: Covalent
Optimization: Chemical
Reaction: Hydrogenation
Max TON: ---
ee: ---
PDB: ---
Notes: TOF = 52.1 h-1 for NAD+

Designed Evolution of Artificial Metalloenzymes: Protein Catalysts Made to Order

Review

Ward, T. R.

Org. Biomol. Chem., 2007, 10.1039/b702068f


Notes: ---

Metatheases: Artificial Metalloproteins for Olefin Metathesis

Review

Okuda, J.

Org. Biomol. Chem., 2016, 10.1039/C6OB01475E


Notes: ---

Selective Oxidation of Aromatic Sulfide Catalyzed by an Artificial Metalloenzyme: New Activity of Hemozymes

Mahy, J.-P.

Org. Biomol. Chem., 2009, 10.1039/b907534h


Metal: Fe
Ligand type: Porphyrin
Host protein: Xylanase A (XynA)
Anchoring strategy: Supramolecular
Optimization: ---
Reaction: Sulfoxidation
Max TON: 145
ee: 40
PDB: ---
Notes: ---