Molecular Design of Heteroprotein Assemblies Providing a Bionanocup as a Chemical Reactor
Small 2008, 4, 50-54, 10.1002/smll.200700855
A bionanocup chemical reactor is constructed from a heteroprotein assembly from bacteriophage T4. The preparation of a stable iron(III) porphyrin–bionanocup composite is described. The hydrophobic cup provides a space suitable for the fixation of low‐water‐solubility iron(III) porphyrins. The application of the iron(III) porphyrin–bionanocup composites for the catalysis of sulfoxidation of thioanisoles is demonstrated (see figure).
Metal: FeLigand type: Maleimide-protoporphyrin IXHost protein: (gp27-gp5)3Anchoring strategy: Cystein-maleimideOptimization: ---Reaction: Peroxidase activityMax TON: ---ee: ---PDB: ---Notes: ---