The Bovine Serum Albumin-2-Phenylpropane-1,2-diolatodioxoosmium(VI) Complex as an Enantioselective Catalyst for cis-Hydroxylation of Alkenes
J. Chem. Soc., Chem. Commun. 1983, 0, 769-770, 10.1039/C39830000769
The 1:1 complex between an osmate ester and bovine serum albumin was found to be effective as an enantioselective catalyst in the cis-hydroxylation of alkenes, affording diols in up to 68% e.e. and turnover of the catalyst with t-butyl hydroperoxide.
Metal: OsLigand type: UndefinedHost protein: Bovine serum albumin (BSA)Anchoring strategy: UndefinedOptimization: ---Reaction: DihydroxylationMax TON: 40ee: 68PDB: ---Notes: ---